Generic Plaquenil: Hydroxychloroquine Insights

Characteristic Details
Brand Name Plaquenil
Active Ingredient Hydroxychloroquine
Available Dosage 200 mg
FDA-Approved Indications Rheumatoid arthritis, Lupus, Malaria prevention
Pregnancy Category Category C
Breastfeeding Risk Low
Toxicity Risk of retinopathy, cardiac complications
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Dosage Information

Generic Plaquenil, known as hydroxychloroquine, is available in a 200 mg tablet form. The dosing regimen depends on the specific indication. In rheumatoid arthritis, a gradual start is common. Often, 400 mg is recommended daily, either once or in two divided doses. For lupus, doses range from 200 to 400 mg daily. The malaria prevention dose is typically 400 mg once a week. It’s taken on the same day each week. In all cases, take it with food or milk to minimize gastric discomfort. Adjustments may be needed based on response and side effects. Always follow healthcare provider guidance for optimal use.

FDA-Approved Indications

Hydroxychloroquine 200 mg holds approval for multiple conditions. It treats autoimmune diseases like rheumatoid arthritis and lupus erythematosus. These conditions benefit from its anti-inflammatory properties. It reduces joint swelling and pain. For lupus, it addresses skin and systemic symptoms. Furthermore, it serves as a prophylactic for malaria. This use is crucial in endemic regions. The drug alters the malaria parasite’s lifecycle, preventing infection. Though FDA-approved for these uses, hydroxychloroquine gained attention for off-label discussions. For official guidance, refer to the FDA’s website.

Pregnancy and Breastfeeding

The use of Generic Plaquenil during pregnancy requires caution. It is a Category C drug. This means animal studies showed adverse effects, but human studies are lacking. Weighing the benefits and risks is crucial. Consultation with a healthcare provider is advised. In breastfeeding, hydroxychloroquine presents a low risk. It passes into breast milk in small amounts. The American Academy of Pediatrics considers it compatible. Monitor the infant for adverse effects. Discuss any concerns with a pediatrician for tailored advice.

Toxicity Risks

Hydroxychloroquine toxicity is a serious concern. Long-term use may lead to retinopathy, affecting vision. Regular eye exams are vital for prevention. The cardiac effects include QT prolongation. This can lead to arrhythmias. Regular monitoring is advisable, especially with high doses. Caution is necessary with other medications affecting the heart. Other side effects include gastrointestinal upset and skin reactions. Any symptoms of toxicity should prompt immediate medical evaluation.

Availability and Prescription Requirements

Non-prescription Generic Plaquenil is unavailable. Its uses and risks necessitate professional oversight. A prescription ensures the proper indication and dose. Monitoring for adverse effects is crucial. Healthcare providers offer guidance on safe use. The current regulatory framework supports these controls for patient safety. Adhering to prescribed regimens enhances therapeutic outcomes. Misuse can lead to resistance, especially concerning malaria. Informed medical decisions optimize benefits while minimizing harm.

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